Necrostatin-7坏死性凋亡抑制剂
| 英文名 | Necrostatin-7 (nec-7) | CAS号 | 351062-08-3 |
| 产品编号 | FSY0313 | 分子式 | C16H10FN5Os2 |
| 产品分类 | 化合物与抑制剂 | 分子量 | 371.41 |
| 纯度 | ≥98% | 储存条件 | -20℃ |
产品描述:
Apoptosis(细胞凋亡)RIP kinase一种坏死细胞死亡通路抑制剂。
Necrostatin-1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.
溶解性:溶于DMSO(>10 mg/mL ) -20°C
包装:10mg 100mg 1g in glass bottle