磷霉素钠

产品简介

Fosfomycin (MK-0955) sodium 是一种能透过血脑屏障的广谱抗生素，不可逆地抑制细胞壁合成的早期阶段。Fosfomycin sodium 对多种细菌具有杀菌活性，这些细菌包括耐多药 (MDR)，广泛耐药 (XDR) 和耐全药 (PDR) 细菌。

体内实验

1、请依序添加每种溶剂： PBS

Solubility: 100 mg/mL (549.39 mM); Clear solution; Need ultrasonic

＜1mg/ml表示微溶或不溶。

体外研究

Fosfomycin sodium is an epoxy antibacterial agent. Compared with other antibacterial agents, it acts by inhibiting the early process of cell wall synthesis.

Fosfomycin sodium has bactericidal activity against a variety of gram-negative and gram-positive pathogens, including broad-spectrum production β-Bacteria of lactamase and

carbapenemase, and against S. aureus strains with an inhibition rate of 90%.

Fosfomycin sodium displays extensive tissue penetration, can be used to research of infections of the CNS, soft tissues, bone, lungs, and abscesses.

体内研究

Fosfomycin sodium (80 mg/kg; i.v.-i.v. or i.v.-p.o.) displays the protective effect on the nephrotoxicity of double beckacin, and is not affected by different administration routes.

保存条件：2-8℃

注意事项：

1、为了您的安全和健康，请穿实验服并戴一次性手套操作。